Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CHIA | Q9BZP6 | 9/20 | 0.39 |
| ▸ | CHIT1 | Q13231 | 8/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.38 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966706 | 0.89 | CHIT1 (0.44) | GRIN2BCHIACHIT1SLC6A4SLC6A2 | |
| SCHEMBL16825796 | 0.82 | CHIA (0.53) | GRIN2BCHIACHIT1SLC6A4SLC6A2 | |
| SCHEMBL3581153 | 0.81 | GRIN2B (0.56) | GRIN2BCHIASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5650537 | 0.79 | GRIN2B (0.41) | GRIN2BCHIACHIT1SLC6A4SLC6A2 | |
| SCHEMBL3041474 | 0.76 | GRIN2B (0.45) | GRIN2BCHIASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23580210 | 0.73 | TACR1 (0.54) | GRIN2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL31016704 | 0.73 | SLC6A4 (0.55) | GRIN2BCHIASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29913509 | 0.73 | SLC6A4 (0.55) | GRIN2BCHIASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27544721 | 0.73 | GRIN2B (0.58) | GRIN2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7473318 | 0.72 | MCHR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |