Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16826397 | 0.85 | ALDH1A1 (0.66) | ALOX15HSD17B10HPGDSMN1; SMN2LMNA | |
| SCHEMBL16825685 | 0.84 | HPGD (0.52) | ALOX15HSD17B10HPGDSMN1; SMN2LMNA | |
| SCHEMBL16825683 | 0.84 | HPGD (0.52) | ALOX15HSD17B10HPGDSMN1; SMN2LMNA | |
| SCHEMBL16826292 | 0.84 | HPGD (0.52) | ALOX15HSD17B10HPGDSMN1; SMN2LMNA | |
| SCHEMBL8020109 | 0.83 | SMN1; SMN2 (0.58) | ALOX15HSD17B10SMN1; SMN2LMNAHTT | |
| SCHEMBL18129134 | 0.83 | KMT2A (0.43) | ALOX15HSD17B10HPGDSMN1; SMN2LMNA | |
| SCHEMBL16846200 | 0.82 | KMT2A (0.56) | ALOX15HSD17B10HPGDSMN1; SMN2LMNA | |
| SCHEMBL16825671 | 0.82 | KMT2A (0.56) | ALOX15HSD17B10HPGDSMN1; SMN2LMNA | |
| SCHEMBL16846161 | 0.82 | KMT2A (0.56) | ALOX15HSD17B10HPGDSMN1; SMN2LMNA | |
| SCHEMBL22221483 | 0.81 | MAPT (0.52) | ALOX15HSD17B10HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082805-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | The Institute For Drug Delivery (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015095701-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | THE INSTITUTE FOR DRUG DELIVERY (US) | 2015-06-25 | — | — | WO | disclosed |