Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16826429 | 0.85 | ALOX15 (0.54) | ALDH1A1KMT2AMEN1GAAALOX15 | |
| SCHEMBL16825743 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1GAAALOX15 | |
| SCHEMBL16825812 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1GAAALOX15 | |
| SCHEMBL16825740 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1GAAALOX15 | |
| SCHEMBL18129178 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1GAAALOX15 | |
| SCHEMBL16825643 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1GAAALOX15 | |
| SCHEMBL16825755 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1GAAALOX15 | |
| SCHEMBL16846219 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1GAAALOX15 | |
| SCHEMBL16825861 | 0.82 | TSHR (0.54) | ALDH1A1KMT2AMEN1GAAHSD17B10 | |
| SCHEMBL16826362 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082805-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | The Institute For Drug Delivery (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015095701-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | THE INSTITUTE FOR DRUG DELIVERY (US) | 2015-06-25 | — | — | WO | disclosed |