Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 3/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16828155 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAKDM4EHPGDHTT | |
| SCHEMBL16828168 | 0.86 | CDK1 (0.45) | SMN1; SMN2LMNAMAPK8HTTNPC1 | |
| SCHEMBL16828189 | 0.85 | CCNA2 (0.37) | SMN1; SMN2LMNAALDH1A1CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL16828217 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAKDM4EHPGDHTT | |
| SCHEMBL16462506 | 0.83 | CCNA2 (0.34) | SMN1; SMN2LMNAALDH1A1CDK1CCNB1 | |
| SCHEMBL16828182 | 0.81 | CDK1 (0.47) | LMNAMAPK8ALDH1A1CDK1CCNB1 | |
| SCHEMBL16481914 | 0.80 | CHUK (0.30) | — | |
| SCHEMBL16482199 | 0.80 | NLRP3 (0.34) | SMN1; SMN2LMNA | |
| SCHEMBL16852182 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAKDM4EHPGDNPC1 | |
| SCHEMBL16828159 | 0.79 | CCNA2 (0.40) | SMN1; SMN2LMNAKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636288-B2 | Means for oxidative dyeing of keratin fibers containing novel tetra-substituted derivatives of pyrimidine | HENKEL AG & CO. KGAA (DE) | 2017-05-02 | — | — | US | disclosed |
| US-9636288-B2 | Means for oxidative dyeing of keratin fibers containing novel tetra-substituted derivatives of pyrimidine | HENKEL AG & CO. KGAA (DE) | 2017-05-02 | — | — | US | disclosed |
| US-9636288-B2 | Means for oxidative dyeing of keratin fibers containing novel tetra-substituted derivatives of pyrimidine | HENKEL AG & CO. KGAA (DE) | 2017-05-02 | — | — | US | disclosed |
| EP-3082751-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | Henkel AG & Co. KGaA (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2016-10-13 | — | — | US | disclosed |
| WO-2015090292-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015090292-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | KRT18, TK1, DPYD | SMN1; SMN2 4219/4885LMNA 1885/4885KDM4E 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.