Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | PNP | P00491 | 3/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22143 | 0.84 | PNP (0.42) | MAPTPNPDYRK1AXDHALDH1A1 | |
| SCHEMBL21805968 | 0.84 | PNP (0.42) | MAPTPNPDYRK1AXDHALDH1A1 | |
| SCHEMBL29733326 | 0.82 | PNP (0.41) | MAPTPNPDYRK1AXDHALDH1A1 | |
| SCHEMBL22144 | 0.82 | MAPT (1.00) | MAPTPNPRPS6KA3ADORA2BDYRK1A | |
| Phosphoric Acid SCHEMBL6461187 | 0.76 | PNP (0.36) | MAPTPNPTHRBALOX15MITF | |
| SCHEMBL447389 | 0.75 | MAPT (0.84) | MAPTPNPRPS6KA3ADORA2BDYRK1A | |
| Hydrochloric Acid SCHEMBL7296117 | 0.73 | MAPT (0.81) | MAPTPNPRPS6KA3ADORA2BDYRK1A | |
| Uracil SCHEMBL19816881 | 0.71 | CRBN (0.47) | MAPTPNPDYRK1AXDHALDH1A1 | |
| SCHEMBL3513712 | 0.71 | MAPT (0.75) | MAPTPNPRPS6KA3ADORA2BDYRK1A | |
| Leucopterin SCHEMBL14080077 | 0.69 | MAPT (0.73) | MAPTPNPDYRK1AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2304044-A1 | METHOD AND KITS FOR REPAIRING NUCLEIC ACID SEQUENCES | General Electric Company (US) | 2011-04-06 | — | — | EP | disclosed |