⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224022 | 0.81 | — | — | |
| SCHEMBL1065557 | 0.77 | — | — | |
| SCHEMBL20943595 | 0.75 | — | — | |
| SCHEMBL252883 | 0.75 | TSHR (0.39) | — | |
| SCHEMBL175574 | 0.75 | TSHR (0.39) | — | |
| SCHEMBL1839325 | 0.72 | — | — | |
| SCHEMBL8291484 | 0.72 | — | — | |
| SCHEMBL9536347 | 0.72 | — | — | |
| SCHEMBL103350 | 0.70 | — | — | |
| SCHEMBL7639808 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101448781-A | Deuterated hepatitis C protease inhibitors | VERTEX PHARMA (US) | 2009-06-03 | — | — | CN | claimed |
| EP-1993994-A2 | DEUTERATED HEPATITIS C PROTEASE INHIBITORS | Vertex Pharmceuticals Incorporated (US) | 2008-11-26 | — | — | EP | claimed |
| WO-2007109080-A2 | DEUTERATED HEPATITIS C PROTEASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-09-27 | — | — | WO | claimed |
| US-7002022-B2 | N-Aryl (thio) anthranilic acid amide derivatives, their preparation and their use as VEGF | NOVARTIS AG (CH) | 2006-02-21 | — | — | US | claimed |
| US-5169856-A | Cholinesterase antagonists | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 1992-12-08 | — | — | US | claimed |
| EP-0096003-A2 | Sulfonyl(thio)ureas, process for their preparation and their use as herbicides and/or growth regulating agents | CIBA-GEIGY AG (CH) | 1983-12-07 | — | — | EP | claimed |
| EP-3896058-A2 | ENANTIONSELECTIVE PROCESSES TO INSECTICIDAL 3-ARYL-3-TRIFLUOROMETHYL-SUBSTITUTED PYRROLIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | disclosed |
| EP-2763963-B1 | ENANTIONSELECTIVE PROCESSES TO INSECTICIDAL 3-ARYL-3-TRIFLUOROMETHYL-SUBSTITUTED PYRROLIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-26 | — | — | EP | disclosed |
| US-10793802-B2 | Mixed phosphorus esters for lubricant applications | THE LUBRIZOL CORPORATION (US) | 2020-10-06 | — | — | US | disclosed |
| EP-1512712-B2 | METHOD OF PRODUCING PARTICLE-SHAPE WATER-ABSORBING RESIN MATERIAL | NIPPON CATALYTIC CHEM IND (JP) | 2019-04-24 | — | — | EP | disclosed |
| US-20170335224-A1 | MIXED PHOSPHORUS ESTERS FOR LUBRICANT APPLICATIONS | THE LUBRIZOL CORPORATION | 2017-11-23 | — | — | US | disclosed |
| EP-2456759-B1 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2017-04-19 | — | — | EP | disclosed |
| EP-3153497-A2 | PESTICIDAL CARBOXAMIDES | Bayer Cropscience AG (DE) | 2017-04-12 | — | — | EP | disclosed |
| WO-2010124845-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-11-04 | — | — | WO | disclosed |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2010-08-26 | — | — | US | disclosed |
| CN-101448781-A | Deuterated hepatitis C protease inhibitors | VERTEX PHARMA (US) | 2009-06-03 | — | — | CN | disclosed |
| EP-1993994-A2 | DEUTERATED HEPATITIS C PROTEASE INHIBITORS | Vertex Pharmceuticals Incorporated (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007109080-A2 | DEUTERATED HEPATITIS C PROTEASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-09-27 | — | — | WO | disclosed |
| EP-0370990-A1 | Herbicidal substituted pyrazoles | MONSANTO COMPANY (US) | 1990-05-30 | — | — | EP | disclosed |
| EP-0295233-A2 | Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides | Monsanto Company (US) | 1988-12-14 | — | — | EP | disclosed |