⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168294 | 0.72 | — | — | |
| SCHEMBL4061442 | 0.70 | — | — | |
| SCHEMBL10337342 | 0.69 | — | — | |
| SCHEMBL8211211 | 0.68 | TSHR (0.32) | — | |
| SCHEMBL7530854 | 0.67 | MAPT (0.41) | — | |
| SCHEMBL3613613 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL16833813 | 0.66 | — | — | |
| SCHEMBL17209859 | 0.61 | — | — | |
| SCHEMBL1246479 | 0.61 | — | — | |
| SCHEMBL16539508 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324109-B1 | 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1993-09-29 | — | — | EP | claimed |
| EP-0324109-A2 | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-07-19 | — | — | EP | claimed |
| WO-1989005811-A1 | NEW 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1989-06-29 | — | — | WO | claimed |
| EP-0324109-B1 | 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5023253-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| US-5023253-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0324109-A2 | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-07-19 | — | — | EP | disclosed |
| EP-0324109-A2 | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-07-19 | — | — | EP | disclosed |
| WO-1989005811-A1 | NEW 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1989-06-29 | — | — | WO | disclosed |
| WO-1989005811-A1 | NEW 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1989-06-29 | — | — | WO | disclosed |