Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1451332 | 0.80 | HSD17B10 (0.30) | — | |
| Acetic Acid SCHEMBL27554638 | 0.79 | — | — | |
| Methylene Chloride SCHEMBL9775394 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL11349685 | 0.71 | — | — | |
| SCHEMBL10871026 | 0.71 | ALDH1A1 (0.46) | — | |
| SCHEMBL27524417 | 0.71 | ALDH1A1 (0.46) | — | |
| SCHEMBL437564 | 0.71 | — | — | |
| SCHEMBL6799285 | 0.71 | ALDH1A1 (0.46) | — | |
| SCHEMBL434958 | 0.71 | — | — | |
| SCHEMBL2815 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180508-B2 | Chemical process for the synthesis of herbicidal pyrazolidinedione compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2021-11-23 | — | — | US | claimed |
| EP-3720861-B1 | CHEMICAL PROCESS FOR THE SYNTHESIS OF HERBICIDAL PYRAZOLIDINEDIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | claimed |
| US-20210171540-A1 | CHEMICAL PROCESS FOR THE SYNTHESIS OF HERBICIDAL PYRAZOLIDINEDIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-06-10 | — | — | US | claimed |
| EP-3720861-A1 | CHEMICAL PROCESS FOR THE SYNTHESIS OF HERBICIDAL PYRAZOLIDINEDIONE COMPOUNDS | Syngenta Participations AG (CH) | 2020-10-14 | — | — | EP | claimed |
| WO-2019110613-A1 | CHEMICAL PROCESS FOR THE SYNTHESIS OF HERBICIDAL PYRAZOLIDINEDIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-13 | — | — | WO | claimed |
| US-20250163010-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-05-22 | — | — | US | disclosed |
| US-20250154124-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-05-15 | — | — | US | disclosed |
| EP-3166923-B1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | SpecGx LLC (US) | 2023-03-15 | — | — | EP | disclosed |
| EP-3995492-A1 | A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | SpecGx LLC (US) | 2022-05-11 | — | — | EP | disclosed |
| EP-3319941-B1 | A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | SpecGx LLC (US) | 2021-12-29 | — | — | EP | disclosed |
| US-11180508-B2 | Chemical process for the synthesis of herbicidal pyrazolidinedione compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2021-11-23 | — | — | US | disclosed |
| EP-3720861-B1 | CHEMICAL PROCESS FOR THE SYNTHESIS OF HERBICIDAL PYRAZOLIDINEDIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | disclosed |
| EP-3720861-A1 | CHEMICAL PROCESS FOR THE SYNTHESIS OF HERBICIDAL PYRAZOLIDINEDIONE COMPOUNDS | Syngenta Participations AG (CH) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019110613-A1 | CHEMICAL PROCESS FOR THE SYNTHESIS OF HERBICIDAL PYRAZOLIDINEDIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-13 | — | — | WO | disclosed |
| US-9914695-B2 | Two-step process for preparing 3-substituted phenylalkylamines | MALLINCKRODT LLC (US) | 2018-03-13 | — | — | US | disclosed |
| US-9556108-B2 | Process for preparing substituted phenylalkanes | MALLINCKRODT LLC (US) | 2017-01-31 | — | — | US | disclosed |
| US-20170008832-A1 | TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | MALLINCKRODT ENTERPRISES LLC | 2017-01-12 | — | — | US | disclosed |
| US-20160009635-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY | 2016-01-14 | — | — | US | disclosed |
| US-7923581-B2 | Process for producing biarylphosphine compound | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20090054690-A1 | Process for producing biarylphosphine compound | NIPPON CHEMICAL INDUSTRIAL CO., LTD. | 2009-02-26 | — | — | US | disclosed |