SCHEMBL16831705

SCHEMBL16831705

Cn1nnc2cc(CCC(=O)O)ccc21

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.57
KEAP1 Q14145 3/20 0.51
HPGD P15428 5/20 0.50
RAB9A P51151 3/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HSD17B10 Q99714 2/20 0.47
POLB P06746 3/20 0.47
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 1/20 0.45
EPHX2 P34913 1/20 0.45
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26802184 0.88 HCAR3 (0.54) HCAR3KEAP1HPGDRAB9AMEN1
SCHEMBL21624765 0.85 HCAR3 (0.60) HCAR3KEAP1HPGDRAB9AMEN1
SCHEMBL13862926 0.80 HPGD (0.49) HCAR3KEAP1HPGDRAB9AMEN1
SCHEMBL16406901 0.79 HCAR3 (0.43) HCAR3KEAP1HPGDRAB9AMEN1
SCHEMBL21409102 0.78 POLB (0.57) HCAR3KEAP1HPGDRAB9AMEN1
SCHEMBL1939333 0.78 HCAR3 (0.54) HCAR3KEAP1HPGDRAB9AMEN1
SCHEMBL30235800 0.77 HCAR3 (0.55) HCAR3KEAP1HPGDRAB9AMEN1
SCHEMBL10287998 0.76 HCAR3 (0.51) HCAR3KEAP1HPGDRAB9AMEN1
SCHEMBL20672106 0.76 POLB (0.46) HCAR3KEAP1HPGDRAB9AMEN1
SCHEMBL19954351 0.76 HPGD (0.49) HCAR3KEAP1HPGDALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113589662-A Composition, stripping liquid, application of stripping liquid in stripping of photoresist or photoresist residues and stripping method 浙江奥首材料科技有限公司 2021-11-02 CN claimed
EP-3083614-A1 NRF2 REGULATORS GlaxoSmithKline Intellectual Property Development Limited (GB) 2016-10-26 EP claimed
WO-2015092713-A1 NRF2 REGULATORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2015-06-25 WO claimed
CN-113589662-B Composition, stripping liquid, application of stripping liquid in stripping of photoresist or photoresist residues and stripping method 浙江奥首材料科技有限公司 2022-07-12 CN disclosed
CN-113589662-A Composition, stripping liquid, application of stripping liquid in stripping of photoresist or photoresist residues and stripping method 浙江奥首材料科技有限公司 2021-11-02 CN disclosed
EP-3083614-A1 NRF2 REGULATORS GlaxoSmithKline Intellectual Property Development Limited (GB) 2016-10-26 EP disclosed
WO-2015092713-A1 NRF2 REGULATORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2015-06-25 WO disclosed