Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862926 | 0.89 | HPGD (0.49) | HPGDKDM4EALDH1A1HSD17B10HCAR3 | |
| SCHEMBL10287998 | 0.82 | HCAR3 (0.51) | HPGDKDM4EALDH1A1HSD17B10HCAR3 | |
| SCHEMBL6765781 | 0.78 | CTNNB1 (0.41) | HCAR3SLC9A1HSD11B1LMNAPLA2G4A | |
| SCHEMBL20672106 | 0.78 | POLB (0.46) | HPGDKDM4EALDH1A1HSD17B10HCAR3 | |
| SCHEMBL9969405 | 0.78 | POLB (0.48) | HPGDKDM4EALDH1A1HSD17B10HCAR3 | |
| SCHEMBL10957998 | 0.77 | PLA2G4A (0.47) | HCAR3SLC9A1RORARORCRORB | |
| SCHEMBL12204543 | 0.77 | HCAR3 (0.54) | HPGDKDM4EALDH1A1HSD17B10HCAR3 | |
| SCHEMBL16406900 | 0.77 | HCAR3 (0.44) | HPGDKDM4EALDH1A1HSD17B10HCAR3 | |
| SCHEMBL904701 | 0.77 | HCAR3 (0.50) | HPGDKDM4EALDH1A1HSD17B10HCAR3 | |
| SCHEMBL3330921 | 0.77 | HCAR3 (0.50) | HPGDKDM4EALDH1A1HSD17B10HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9913913-B2 | Method for preparing a polymeric reagent | NEKTAR THERAPEUTICS (US) | 2018-03-13 | — | — | US | disclosed |