SCHEMBL1683247

SCHEMBL1683247

Brc1ccnc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.40
HTR5A P47898 1/20 0.40
TDO2 P48775 1/20 0.40
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
CDK5 Q00535 1/20 0.39
CDK5R1 Q15078 1/20 0.39
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
CDK2 P24941 2/20 0.37
DCLK1 O15075 1/20 0.37
PRKD3 O94806 1/20 0.37
MAP4K4 O95819 1/20 0.37
CHEK2 O96017 1/20 0.37
CSF1R P07333 1/20 0.37
FER P16591 1/20 0.37
MARK3 P27448 1/20 0.37
FLT4 P35916 1/20 0.37
FLT3 P36888 1/20 0.37
MAPK9 P45984 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6876361 0.83 KDM4E (0.43) CDK5CDK5R1CAMK2GDYRK1AMAPK1
SCHEMBL7264143 0.81 HTR2B (0.41) HTR2BHTR5ATDO2PDE3BPDE3A
SCHEMBL28303419 0.79 MAPK1 (0.37) CDK5PRKD3MAP4K4CSF1RCLK2
SCHEMBL28491380 0.78 NPC1 (0.44) TDO2PTGS1PTGS2MAPK1ALDH1A1
SCHEMBL28145706 0.78 CDK5 (0.45) HTR2BHTR5ATDO2PDE3BPDE3A
SCHEMBL27867911 0.78 NQO2 (0.41) HTR2BHTR5ATDO2PDE3BPDE3A
SCHEMBL31187041 0.77 CYP2A6 (0.39) PTGS1PTGS2MAPK1ALDH1A1KDM4E
SCHEMBL10381277 0.77 HTR2B (0.41) HTR2BHTR5ATDO2PDE3BPDE3A
SCHEMBL996432 0.77 CCNA2 (0.45) HTR2BHTR5ATDO2PDE3BPDE3A
SCHEMBL28317500 0.76 CDK2 (0.52) CDK5PTGS1PTGS2CDK2DCLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119662625-A Conjugated microporous polymer-chlorella complex, preparation method thereof and application thereof in treatment of organic pollutants in sewage 中国科学院生态环境研究中心 2025-03-21 CN disclosed
CN-106749236-B It is a kind of with the aza toroid electroluminescent organic material of dibenzocycloheptene structure and its application 中节能万润股份有限公司 2019-01-29 CN disclosed
US-8530063-B2 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2013-09-10 US disclosed
US-20120205636-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-08-16 US disclosed
WO-2011049325-A2 NOVEL COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES INC. (KR) 2011-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120205636-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME PPOX, AOX1, DDT HTR2B 4077/4885HTR5A 4675/4885TDO2 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.