SCHEMBL16836638

SCHEMBL16836638

CCCCCCCCCCCCCOc1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 5/20 0.70
TP53 P04637 1/20 0.64
TSHR P16473 1/20 0.64
PLA2G4B P0C869 4/20 0.62
PLA2G2A P14555 1/20 0.59
RARB P10826 3/20 0.59
PLK1 P53350 1/20 0.56
PLA2G4A P47712 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7272804 1.00 PTPN11 (0.70) PTPN11TP53TSHRPLA2G4BPLA2G2A
SCHEMBL8179881 1.00 PTPN11 (0.70) PTPN11TP53TSHRPLA2G4BPLA2G2A
SCHEMBL8085899 0.98 PTPN11 (0.68) PTPN11TP53TSHRPLA2G4BPLA2G2A
SCHEMBL21543820 0.95 PTPN11 (0.62) PTPN11TP53TSHRPLA2G4BPLA2G2A
SCHEMBL31186568 0.92 PTPN11 (0.57) PTPN11TP53TSHRPLA2G4BRARB
SCHEMBL28870271 0.90 PTPN11 (0.62) PTPN11TP53TSHRPLA2G4BPLA2G2A
SCHEMBL28280526 0.90 PTPN11 (0.62) PTPN11TP53TSHRPLA2G4BPLA2G2A
SCHEMBL8974262 0.89 PTPN11 (0.64) PTPN11TP53TSHRPLA2G4BPLA2G2A
SCHEMBL5492191 0.89 PTPN11 (0.64) PTPN11TP53TSHRPLA2G4BPLA2G2A
SCHEMBL7820620 0.89 PTPN11 (0.64) PTPN11TP53TSHRPLA2G4BPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3083878-B1 COMPOSITE NANOPARTICLES INCLUDING A PHTHALIC ACID DERIVATIVE 3M INNOVATIVE PROPERTIES CO (US) 2018-10-03 EP disclosed
US-10066159-B2 Composite nanoparticles including a phthalic acid derivative 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-09-04 US disclosed
EP-3083878-A1 COMPOSITE NANOPARTICLES INCLUDING A PHTHALIC ACID DERIVATIVE 3M Innovative Properties Company (US) 2016-10-26 EP disclosed
US-20160298029-A1 COMPOSITE NANOPARTICLES INCLUDING A PHTHALIC ACID DERIVATIVE 3M INNOVATIVE PROPERTIES COMPANY 2016-10-13 US disclosed
WO-2015094646-A1 COMPOSITE NANOPARTICLES INCLUDING A PHTHALIC ACID DERIVATIVE 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-06-25 WO disclosed