Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16836638 | 0.98 | PTPN11 (0.70) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL7272804 | 0.98 | PTPN11 (0.70) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL8179881 | 0.98 | PTPN11 (0.70) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL21543820 | 0.97 | PTPN11 (0.62) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL8146895 | 0.90 | KMT2A (0.58) | PTPN11TP53TSHRRARBPLK1 | |
| SCHEMBL31186568 | 0.90 | PTPN11 (0.57) | PTPN11TP53TSHRPLA2G4BRARB | |
| SCHEMBL28870271 | 0.88 | PTPN11 (0.62) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL28280526 | 0.88 | PTPN11 (0.62) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL5492191 | 0.87 | PTPN11 (0.64) | PTPN11TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL8974262 | 0.87 | PTPN11 (0.64) | PTPN11TP53TSHRPLA2G4BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2021-06-01 | — | — | US | disclosed |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2019-11-14 | — | — | US | disclosed |
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | TAS2R20, BLVRB, FDPS | PTPN11 257/4885TP53 2851/4885TSHR 3925/4885 |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | TAS2R20, BLVRB, NOTUM | PTPN11 270/4885TP53 2824/4885TSHR 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.