Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.58 |
| ▸ | TP53 | P04637 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16903190 | 0.91 | MAPT (0.54) | MAPTTP53LMNATSHRALDH1A1 | |
| SCHEMBL16768716 | 0.89 | MAPT (0.58) | MAPTTP53LMNATSHRALDH1A1 | |
| SCHEMBL16903074 | 0.89 | MAPT (0.51) | MAPTTP53LMNATSHRALDH1A1 | |
| SCHEMBL16903077 | 0.88 | MAPT (0.51) | MAPTTP53LMNATSHRALDH1A1 | |
| SCHEMBL15276983 | 0.87 | MAPT (0.56) | MAPTTP53LMNATSHRALDH1A1 | |
| SCHEMBL15076342 | 0.86 | MAPT (0.64) | MAPTTP53LMNATSHRALDH1A1 | |
| SCHEMBL21623228 | 0.85 | MAPT (0.66) | MAPTTP53LMNATSHRALDH1A1 | |
| SCHEMBL21624587 | 0.85 | MAPT (0.66) | MAPTTP53LMNATSHRALDH1A1 | |
| SCHEMBL16903187 | 0.83 | MAPT (0.59) | MAPTTP53LMNATSHRALDH1A1 | |
| SCHEMBL19367498 | 0.83 | MAPT (0.63) | MAPTTP53LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9061008-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2015-06-23 | — | — | US | disclosed |