Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 10/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CD40 | P25942 | 1/20 | 0.38 |
| ▸ | CD40LG | P29965 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838463 | 0.92 | PHLPP2 (0.42) | PHLPP2ENPP2THRBCD40CD40LG | |
| SCHEMBL14388762 | 0.91 | CD40 (0.44) | ENPP2THRBCD40CD40LGCA2 | |
| SCHEMBL14388938 | 0.91 | CD40 (0.44) | ENPP2THRBCD40CD40LGCA2 | |
| SCHEMBL14388926 | 0.91 | THRB (0.42) | ENPP2THRBCD40CD40LGCA2 | |
| SCHEMBL14346733 | 0.89 | ENPP2 (0.40) | PHLPP2ENPP2THRBCD40CD40LG | |
| SCHEMBL16838426 | 0.88 | ENPP2 (0.38) | PHLPP2ENPP2CD40CD40LGCA2 | |
| SCHEMBL14346573 | 0.88 | PTPN1 (0.40) | PHLPP2ENPP2THRBCD40CD40LG | |
| SCHEMBL14388760 | 0.88 | CD40 (0.40) | ENPP2THRBCD40CD40LGCA2 | |
| SCHEMBL16838480 | 0.87 | ENPP2 (0.41) | PHLPP2ENPP2THRBCD40CD40LG | |
| SCHEMBL14388846 | 0.87 | CD40 (0.39) | ENPP2THRBCD40CD40LGCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391683-B1 | FIBER-REACTIVE COPPER COMPLEX DISAZO DYES | DYSTAR COLOURS DISTRIB GMBH (DE) | 2017-03-29 | — | — | EP | disclosed |
| US-9062208-B2 | Fiber-reactive copper complex disazo dyes | DYSTAR COLOURS DISTRIBUTION GMBH (DE) | 2015-06-23 | — | — | US | disclosed |