Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16820956 | 0.91 | ACACB (0.36) | L3MBTL1MAPTACACBPRSS1CTSG | |
| SCHEMBL16820767 | 0.88 | ACACB (0.38) | L3MBTL1ACACBPRSS1CTSGCTRB1 | |
| SCHEMBL16820768 | 0.88 | ACACB (0.38) | L3MBTL1ACACBPRSS1CTSGCTRB1 | |
| SCHEMBL16820822 | 0.83 | ACACB (0.38) | L3MBTL1MAPTACACBLMNATAS1R3 | |
| SCHEMBL16820821 | 0.83 | ACACB (0.38) | L3MBTL1MAPTACACBLMNATAS1R3 | |
| SCHEMBL15235729 | 0.83 | CA2 (0.39) | L3MBTL1MAPTACACBLMNATAS1R3 | |
| SCHEMBL16820869 | 0.82 | ACACB (0.35) | L3MBTL1ALDH1A1ACACBPRSS1CTSG | |
| SCHEMBL16820800 | 0.82 | ACACB (0.35) | L3MBTL1ALDH1A1ACACBPRSS1CTSG | |
| SCHEMBL16820803 | 0.82 | ACACB (0.35) | L3MBTL1ALDH1A1ACACBPRSS1CTSG | |
| SCHEMBL16820798 | 0.82 | ACACB (0.35) | L3MBTL1ALDH1A1ACACBPRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175530-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175530-A1 | ANTIBACTERIAL AGENTS | MRPL21, ABCB11, LSS | L3MBTL1 2949/4885ALDH1A1 1168/4885MAPT 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.