Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 6/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | KRAS | P01116 | 5/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16840873 | 0.93 | HINT1 (0.48) | HINT1NT5ETGM2TAS1R3TAS1R1 | |
| SCHEMBL22577507 | 0.90 | HINT1 (0.51) | HINT1NT5ETGM2TAS1R3TAS1R1 | |
| SCHEMBL25813664 | 0.90 | HINT1 (0.51) | HINT1NT5ETGM2TAS1R3TAS1R1 | |
| SCHEMBL27216242 | 0.90 | HINT1 (0.51) | HINT1NT5ETGM2TAS1R3TAS1R1 | |
| SCHEMBL24377170 | 0.90 | HINT1 (0.58) | HINT1NT5ETGM2TAS1R3TAS1R1 | |
| SCHEMBL26209875 | 0.88 | HINT1 (0.50) | HINT1NT5ETGM2TAS1R3TAS1R1 | |
| SCHEMBL25613000 | 0.88 | HINT1 (0.49) | HINT1NT5ETGM2TAS1R3TAS1R1 | |
| SCHEMBL16844106 | 0.88 | HINT1 (0.49) | HINT1NT5ETGM2TAS1R3TAS1R1 | |
| SCHEMBL26211531 | 0.87 | HINT1 (0.49) | HINT1NT5ETGM2TAS1R3TAS1R1 | |
| SCHEMBL20017125 | 0.86 | STING1 (0.49) | HINT1NT5ETGM2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688715-B2 | Synthetic pGpG analogs, methods of preparation and methods of use | Temple University—Of the Commonwealth System of Higher Education (US) | 2017-06-27 | — | — | US | disclosed |
| US-20150175649-A1 | SYNTHETIC pGpG ANALOGS, METHODS OF PREPARATION AND METHODS OF USE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175649-A1 | SYNTHETIC pGpG ANALOGS, METHODS OF PREPARATION AND METHODS OF USE | MRPL21, PGLS, CFTR | HINT1 1449/4885NT5E 505/4885TGM2 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.