SCHEMBL1684101

SCHEMBL1684101

CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)/C=C/c2ccc(C=C3SC(=O)NC3=O)cc2)N(C(=O)c2ccccc2C(=O)c2ccc(F)cc2F)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLA2G4A P47712 18/20 1.00
PLA2G4C Q9UP65 2/20 0.54
PLA2G6 O60733 1/20 0.53
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22222832 1.00 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6SLC6A2SLC6A4
SCHEMBL29380622 1.00 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6SLC6A2SLC6A4
SCHEMBL29862419 1.00 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6SLC6A2SLC6A4
SCHEMBL16908822 1.00 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6SLC6A2SLC6A4
SCHEMBL19689390 1.00 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6SLC6A2SLC6A4
SCHEMBL1684102 1.00 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6SLC6A2SLC6A4
SCHEMBL22222829 1.00 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6SLC6A2SLC6A4
SCHEMBL22187692 1.00 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6SLC6A2SLC6A4
SCHEMBL22222878 0.93 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6
SCHEMBL3690078 0.93 PLA2G4A (1.00) PLA2G4APLA2G4CPLA2G6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120232031-A1 INJECTABLE FORMULATIONS FOR INTRA-ARTICULAR OR PERI-ARTICULAR ADMINISTRATION PANMIRA PHARMACEUTICALS, LLC (US) 2012-09-13 US claimed
EP-2490689-A2 INJECTABLE FORMULATIONS FOR INTRA- ARTICULAR OR PERI-ARTICULAR ADMINISTRATION Panmira Pharmaceuticals, LLC (US) 2012-08-29 EP claimed
WO-2011049979-A2 INJECTABLE FORMULATIONS FOR INTRA- ARTICULAR OR PERI-ARTICULAR ADMINISTRATION AMIRA PHARMACEUTICALS, INC. (US) 2011-04-28 WO claimed
US-11000506-B2 Envenomation therapies and related pharmaceutical compositions, systems and kits OPHIREX, INC. (US) 2021-05-11 US disclosed
US-20170354642-A1 ENVENOMATION THERAPIES AND RELATED PHARMACEUTICAL COMPOSITIONS, SYSTEMS AND KITS OPHIREX INC (US) 2017-12-14 US disclosed
US-20120232031-A1 INJECTABLE FORMULATIONS FOR INTRA-ARTICULAR OR PERI-ARTICULAR ADMINISTRATION PANMIRA PHARMACEUTICALS, LLC (US) 2012-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11000506-B2 Envenomation therapies and related pharmaceutical compositions, systems and kits PLA2R1, PLA2G12A, ACHE PLA2G4A 9/4885PLA2G4C 19/4885PLA2G6 28/4885
US-20170354642-A1 ENVENOMATION THERAPIES AND RELATED PHARMACEUTICAL COMPOSITIONS, SYSTEMS AND KITS PLA2R1, PLA2G12A, ACHE PLA2G4A 9/4885PLA2G4C 19/4885PLA2G6 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.