SCHEMBL1684230

SCHEMBL1684230

CCCCCCC(Cc1ccccc1)C(C)(C)N

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CSNK1E P49674 1/20 0.55
▸ MMP2 P08253 14/20 0.42
▸ MMP1 P03956 9/20 0.42
▸ MMP3 P08254 9/20 0.42
▸ HTR2A P28223 1/20 0.42
▸ KCNH2 Q12809 1/20 0.41
▸ MMP7 P09237 4/20 0.40
▸ SIGMAR1 Q99720 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8387575 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8385145 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL2392222 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8386222 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL25283495 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL25287896 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8383203 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL2394133 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL337801 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8381675 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4048751-B1 POLISHING COMPOSITION AND METHOD WITH HIGH SELECTIVITY FOR SILICON NITRIDE AND POLYSILICON OVER SILICON OXIDE CMC MAT LLC (US) 2025-03-19 — — EP claimed
EP-3503927-B1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT UNIV CALIFORNIA (US) 2025-02-19 — — EP claimed
CN-118613517-A Preparation and use of polyisocyanates containing iminooxadiazinedione groups 巴斯夫欧洲公司 2024-09-06 — — CN claimed
WO-2024165361-A1 PREPARATION OF POLYISOCYANATES CONTAINING IMINOOXADIAZINEDIONE GROUPS AND THEIR USE BASF SE (DE) 2024-08-15 — — WO claimed
WO-2023138938-A1 PREPARATION OF POLYISOCYANATES CONTAINING IMINOOXADIAZINEDIONE GROUPS AND THEIR USE BASF SE (DE) 2023-07-27 — — WO claimed
EP-4146765-B1 A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG (DE) 2023-07-05 — — EP claimed
CN-109789216-B Topical skin treatment formulations based on ionic species 加利福尼亚大学董事会 2023-05-23 — — CN claimed
EP-4048751-A1 POLISHING COMPOSITION AND METHOD WITH HIGH SELECTIVITY FOR SILICON NITRIDE AND POLYSILICON OVER SILICON OXIDE CMC Materials, Inc. (US) 2022-08-31 — — EP claimed
CN-114599753-A Polishing composition and method with high selectivity for silicon nitride and polysilicon versus silicon oxide CMC材料股份有限公司 2022-06-07 — — CN claimed
US-20210162050-A1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-06-03 — — US claimed
EP-0794186-A1 The preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-10 — — EP claimed
US-5663396-A Preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-02 — — US claimed
EP-0599188-B1 Trans and CIS traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity LIFEGROUP SPA (IT) 1997-08-06 — — EP claimed
US-5583245-A Preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-12-10 — — US claimed
US-5567716-A FOR THE THERAPEUTIC TREATMENT OF CUTANEOUS PATHOLOGIES LIFEGROUP S.P.A. (IT) 1996-10-22 — — US claimed
US-5468893-A Preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-11-21 — — US claimed
US-5405985-A Preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-04-11 — — US claimed
EP-0599188-A1 Trans and CIS traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity LIFEGROUP S.p.A. (IT) 1994-06-01 — — EP claimed
EP-0579207-A1 Charge control agent and positively chargeable toner for developing electrostatic images ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1994-01-19 — — EP claimed
US-4433164-A HYDROHALIDE; PALLADIUM CATALYST; AMMONIUM, PHOSPHONIUM OR ARSONIUM COMPOUND RHONE-POULENC INDUSTRIES (FR) 1984-02-21 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210162050-A1 TOPICAL FORMULATIONS BASED ON IONIC SPECIES FOR SKIN TREATMENT CUTA, KRT18, SLC38A7 CSNK1E 419/4885MMP2 201/4885MMP1 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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