SCHEMBL1684243

SCHEMBL1684243

CC(Cc1ccccc1)C(C)(C)N

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.56
SIGMAR1 Q99720 4/20 0.56
SLC6A2 P23975 3/20 0.56
MAOA P21397 1/20 0.56
SLC6A4 P31645 1/20 0.56
SLC6A3 Q01959 1/20 0.56
CYP2A6 P11509 1/20 0.56
ADORA2A P29274 1/20 0.56
ADORA1 P30542 1/20 0.56
CYP2D6 P10635 1/20 0.52
EPHX1 P07099 1/20 0.48
SLC18A2 Q05940 1/20 0.47
TRPA1 O75762 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2389403 0.98 TAAR1 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Hydrochloric Acid SCHEMBL17710411 0.98 TAAR1 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Water SCHEMBL7069224 0.98 TAAR1 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Isobutylbenzene SCHEMBL6544201 0.80 TAAR1 (0.58) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL25283903 0.79 TAAR1 (0.52) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL8915534 0.79 TAAR1 (0.52) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL23867974 0.79 TAAR1 (0.52) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL1619118 0.78 SLC6A2 (0.56) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL8380077 0.78 TAAR1 (0.50) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL9154023 0.78 CYP2D6 (0.57) TAAR1SIGMAR1SLC6A2MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4146765-B1 A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG (DE) 2023-07-05 EP claimed
CN-108148394-B Storage-stable one-component polyurethane prepregs from polyurethane compositions and moldings produced therefrom 赢创运营有限公司 2021-12-28 CN claimed
EP-3081283-B1 METHOD FOR REMOVING SOX IN GAS BY USING ETHYLENE GLYCOL COMPLEX SOLUTION BEIJING BOYUAN HENGSHENG HIGH TECH CO LTD (CN) 2020-10-21 EP claimed
EP-0839816-B1 The preparation of sulfur-containing organosilicon compounds GOODYEAR TIRE & RUBBER (US) 2004-04-28 EP claimed
EP-0794186-B1 The preparation of sulfur-containing organosilicon compounds GOODYEAR TIRE & RUBBER (US) 2003-05-28 EP claimed
US-6465670-B2 SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST THE GOODYEAR TIRE & RUBBER COMPANY 2002-10-15 US claimed
US-20020022085-A1 Preparation of surface modified silica GOODYEAR TIRE & RUBBER COMPANY, THE 2002-02-21 US claimed
US-6172251-B1 USING ORGANOSILICON COMPOUNDS THE GOODYEAR TIRE & RUBBER COMPANY 2001-01-09 US claimed
EP-0839816-A1 The preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-05-06 EP claimed
EP-0794186-A1 The preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-10 EP claimed
US-5663396-A Preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-02 US claimed
US-5583245-A Preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-12-10 US claimed
US-5468893-A Preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-11-21 US claimed
US-5405985-A Preparation of sulfur-containing organosilicon compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-04-11 US claimed
US-4433164-A HYDROHALIDE; PALLADIUM CATALYST; AMMONIUM, PHOSPHONIUM OR ARSONIUM COMPOUND RHONE-POULENC INDUSTRIES (FR) 1984-02-21 US claimed
US-20240353412-A1 A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG (DE) 2024-10-24 US disclosed
EP-4146765-B1 A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG (DE) 2023-07-05 EP disclosed
EP-0031784-A2 Process for preparing ethyl carboxylates from their lower homologues RHONE-POULENC CHIMIE DE BASE (FR) 1981-07-08 EP disclosed
EP-0022735-A1 Process for the preparation of acetaldehyde RHONE-POULENC CHIMIE DE BASE (FR) 1981-01-21 EP disclosed
EP-0022038-A1 Process for the homologation of methanol RHONE-POULENC CHIMIE DE BASE (FR) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020022085-A1 Preparation of surface modified silica OSTC, SAMM50, SSRP1 TAAR1 1485/4885SIGMAR1 99/4885SLC6A2 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.