SCHEMBL8915534

SCHEMBL8915534

CC(Cc1ccccc1)C(N)(N)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.52
SIGMAR1 Q99720 4/20 0.52
SLC6A2 P23975 3/20 0.52
MAOA P21397 1/20 0.52
SLC6A4 P31645 1/20 0.52
SLC6A3 Q01959 1/20 0.52
CYP2A6 P11509 1/20 0.52
ADORA2A P29274 1/20 0.52
ADORA1 P30542 1/20 0.52
CYP2D6 P10635 1/20 0.48
EPHX1 P07099 1/20 0.45
TRPA1 O75762 3/20 0.44
SLC18A2 Q05940 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL5091831 0.82 TAAR1 (0.50) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Hydrochloric Acid SCHEMBL5085050 0.82 TAAR1 (0.50) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Iodide SCHEMBL5092961 0.82 TAAR1 (0.50) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL9860258 0.79 TAAR1 (0.56) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL1684243 0.79 TAAR1 (0.56) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL8761557 0.78 SLC6A2 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL2389403 0.78 TAAR1 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Water SCHEMBL7069224 0.78 TAAR1 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Hydrochloric Acid SCHEMBL17710411 0.78 TAAR1 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL25283903 0.76 TAAR1 (0.52) TAAR1SIGMAR1SLC6A2MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066238-A Preparation of cannabichromenes and related cannabinoids 海湾医学公司 2022-09-16 CN claimed
CN-117157281-A Targeted delivery of 1,2,4, 5-tetraoxacompounds and uses thereof 西湖大学 2023-12-01 CN disclosed
CN-115066238-A Preparation of cannabichromenes and related cannabinoids 海湾医学公司 2022-09-16 CN disclosed
CN-1220262-A 7-phenyl-1,4-stable derivative, its preparing method and medicine containing said compound SOLVAY PHARM GMBH (DE) 1999-06-23 CN disclosed
US-5677350-A Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1997-10-14 US disclosed
WO-1996040096-A1 INHIBITION OF CANCER CELL GROWTH, PROLIFERATION AND METASTASIS USING N,N'-DIBENZYL-α,φ-DIAMINOALKANES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1996-12-19 WO disclosed