SCHEMBL23867974

SCHEMBL23867974

C[C@@H](Cc1ccccc1)C(C)(C)CN

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 6/20 0.52
SIGMAR1 Q99720 4/20 0.52
SLC6A2 P23975 3/20 0.52
MAOA P21397 1/20 0.52
SLC6A4 P31645 1/20 0.52
SLC6A3 Q01959 1/20 0.52
CYP2A6 P11509 1/20 0.52
ADORA2A P29274 1/20 0.52
ADORA1 P30542 1/20 0.52
CYP2D6 P10635 2/20 0.48
EPHX1 P07099 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
PRMT1 Q99873 1/20 0.44
SLC18A2 Q05940 1/20 0.44
TRPA1 O75762 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1684243 0.79 TAAR1 (0.56) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL2389403 0.78 TAAR1 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Water SCHEMBL7069224 0.78 TAAR1 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Hydrochloric Acid SCHEMBL17710411 0.78 TAAR1 (0.54) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL8380077 0.75 TAAR1 (0.50) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL6546209 0.73 SIGMAR1 (0.48) TAAR1SIGMAR1SLC6A2MAOASLC6A4
Isobutylbenzene SCHEMBL6544201 0.72 TAAR1 (0.58) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL9947015 0.72 SIGMAR1 (0.52) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL9562321 0.72 TAAR1 (0.47) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL8915534 0.72 TAAR1 (0.52) TAAR1SIGMAR1SLC6A2MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210304851-A1 COMPUTER-BASED METHOD FOR DETERMINING A SUNSCREEN COMPOSITION COMPRISING A PLURALITY OF UV FILTER SUBSTANCES DSM IP ASSETS B.V. (NL) 2021-09-30 US disclosed