SCHEMBL16844151

SCHEMBL16844151

O=C1CC/C(=C\C2=Cc3ccccc3CC2)O1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
NISCH Q9Y2I1 1/20 0.33
KDM1A O60341 1/20 0.33
GPR84 Q9NQS5 1/20 0.32
CYP19A1 P11511 1/20 0.31
CES1 P23141 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
MIF P14174 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4265228 0.75 KDM1A (0.42) CYP11B1CYP11B2NISCHKDM1AGPR84
SCHEMBL29648416 0.75 KDM1A (0.42) CYP11B1CYP11B2NISCHKDM1AGPR84
SCHEMBL3083425 0.70 CYP1A2 (0.48) MAOBMIF
SCHEMBL2531349 0.68 GPR84 (0.41) CYP11B1CYP11B2NISCHKDM1AGPR84
SCHEMBL2531348 0.68 GPR84 (0.41) CYP11B1CYP11B2NISCHKDM1AGPR84
SCHEMBL29190731 0.68 TSHR (0.58) CES1MAOAMAOBCYP2A6
SCHEMBL31510121 0.68 TSHR (0.58) CES1MAOAMAOBCYP2A6
SCHEMBL2069862 0.68 KDM1A (0.42) CYP11B1CYP11B2NISCHKDM1AGPR84
SCHEMBL4264349 0.67 HCAR2 (0.44) CYP11B1CYP11B2KDM1ACYP19A1MAOA
SCHEMBL4270776 0.67 HCAR2 (0.44) CYP11B1CYP11B2KDM1ACYP19A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1693706-B1 Photosensitive lithographic printing plate containing a mercapto compound FUJIFILM CORP (JP) 2015-06-24 EP disclosed