Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18493219 | 0.67 | MIF (0.65) | SLC16A3MIFPFKFB3MAOBMAOA | |
| SCHEMBL16674791 | 0.66 | SLC16A3 (0.58) | SLC16A3MIFMAOBAPPMAOA | |
| SCHEMBL16312153 | 0.66 | SLC16A3 (0.63) | SLC16A3MIFMAOBMAOAKDM4E | |
| SCHEMBL16674787 | 0.65 | SLC16A3 (0.62) | SLC16A3MIFMAOBMAOAKDM4E | |
| SCHEMBL10434168 | 0.63 | SLC16A3 (0.66) | SLC16A3MIFMAOBAPPMAOA | |
| SCHEMBL21301331 | 0.63 | SLC16A3 (0.38) | SLC16A3MIFPFKFB3MAOBAPP | |
| SCHEMBL16674796 | 0.63 | SLC16A3 (0.56) | SLC16A3MIFMAOBAPPMAOA | |
| SCHEMBL28868214 | 0.63 | ALDH1A1 (0.54) | SLC16A3MIFPFKFB3MAOBKDM4E | |
| SCHEMBL15138692 | 0.62 | SLC16A3 (0.81) | SLC16A3MAOBMAOAKDM4ECA12 | |
| SCHEMBL15069455 | 0.62 | MIF (0.56) | SLC16A3MIFKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015095449-A1 | METHODS FOR MODULATING THE AMOUNT RNA TRANSCRIPTS | PTC THERAPEUTICS, INC. (US) | 2015-06-25 | — | — | WO | disclosed |