Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21301458 | 0.71 | SLC16A3 (0.35) | SLC16A3MAPT | |
| SCHEMBL16844833 | 0.63 | SLC16A3 (0.38) | SLC16A3MAOBAPPKDM4EALDH1A1 | |
| SCHEMBL23010842 | 0.62 | ADRB1 (0.54) | SLC16A3CYP1A2CYP2C19 | |
| SCHEMBL16312153 | 0.62 | SLC16A3 (0.63) | SLC16A3MAOBMEN1USP2CYP1A2 | |
| SCHEMBL21301310 | 0.62 | SLC16A3 (0.38) | SLC16A3MAOBMEN1USP2CYP1A2 | |
| SCHEMBL18493219 | 0.61 | MIF (0.65) | SLC16A3MAOBUSP2MAPTKMT2A | |
| SCHEMBL16674787 | 0.61 | SLC16A3 (0.62) | SLC16A3MAOBMEN1USP2CYP1A2 | |
| SCHEMBL28868214 | 0.61 | ALDH1A1 (0.54) | SLC16A3MAOBMEN1USP2CYP1A2 | |
| SCHEMBL15067426 | 0.61 | MAOB (0.61) | SLC16A3MAOB | |
| SCHEMBL16674791 | 0.61 | SLC16A3 (0.58) | SLC16A3MAOBCYP2C19APPMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797592-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-08-28 | — | — | EP | disclosed |