Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 13/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL18185567 | 0.95 | ADRA1A (0.45) | ADRA1AROCK2ROCK1L3MBTL1L3MBTL3 | |
| SCHEMBL16845162 | 0.91 | MAPK14 (0.52) | ADRA1AROCK2ROCK1 | |
| Trifluoroacetic Acid SCHEMBL18185637 | 0.88 | MAPK14 (0.51) | ADRA1AROCK2ROCK1ALDH1A1KDM4E | |
| SCHEMBL16845091 | 0.81 | ADRA1A (0.62) | ADRA1AL3MBTL1L3MBTL3ALDH1A1KDM4E | |
| SCHEMBL16845151 | 0.80 | ADRA1A (0.54) | ADRA1AL3MBTL1L3MBTL3ALDH1A1KDM4E | |
| SCHEMBL16845209 | 0.79 | ADRA1A (0.52) | ADRA1AL3MBTL1L3MBTL3ALDH1A1KDM4E | |
| SCHEMBL16823944 | 0.76 | ADRA1A (0.70) | ADRA1AL3MBTL1L3MBTL3 | |
| Trifluoroacetic Acid SCHEMBL18185575 | 0.76 | ADRA1A (0.57) | ADRA1AL3MBTL1L3MBTL3ALDH1A1KDM4E | |
| SCHEMBL16845095 | 0.76 | EPHX2 (0.49) | ADRA1AL3MBTL1L3MBTL3ALDH1A1KDM4E | |
| SCHEMBL16845164 | 0.76 | ADRA1A (0.51) | ADRA1AL3MBTL1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318866-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160318866-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-11-03 | — | — | US | disclosed |
| WO-2015091415-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES AS ADRENORECEPTOR ALPHA 2C ANTAGONISTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318866-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | TNNI3, TNNC1, FABP3 | ADRA1A 1241/4885ROCK2 4482/4885ROCK1 4506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.