⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37555 | 0.84 | — | — | |
| SCHEMBL167182 | 0.84 | — | — | |
| SCHEMBL5158 | 0.63 | — | — | |
| SCHEMBL15775089 | 0.62 | — | — | |
| SCHEMBL61121 | 0.62 | — | — | |
| SCHEMBL11683805 | 0.61 | KDM1A (0.45) | — | |
| SCHEMBL11071014 | 0.61 | KDM1A (0.35) | — | |
| SCHEMBL1904517 | 0.61 | KDM1A (0.50) | — | |
| SCHEMBL4137295 | 0.61 | — | — | |
| SCHEMBL11071002 | 0.61 | KDM1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130498-A1 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSHES INSTITUT FUR ERNAHRUNGSFORSCHUNG POTSDAM- REHBRUCKE (DE) | 2010-05-27 | — | — | US | claimed |
| EP-2132564-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke Stiftung des Öffentlichen Rechts (DE) | 2009-12-16 | — | — | EP | claimed |
| WO-2008119527-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POSTDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) | 2008-10-09 | — | — | WO | claimed |
| EP-1975611-A1 | Agonists of bitter taste receptors and uses thereof | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand (DE) | 2008-10-01 | — | — | EP | claimed |
| US-10253236-B2 | Environmental friendly well treatment fluids comprising an ester | AMRIL AG (CH) | 2019-04-09 | — | — | US | disclosed |
| EP-3024910-B1 | ENVIRONMENTAL FRIENDLY WELL TREATMENT FLUIDS COMPRISING AN ESTER | AMRIL AG (CH) | 2018-12-12 | — | — | EP | disclosed |
| EP-2861675-B1 | DISPERSING AGENT COMPRISING FILLERS OR PIGMENTS | AMRIL AG (CH) | 2018-09-05 | — | — | EP | disclosed |
| EP-2137530-B1 | ANTAGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INST FUER ERNAEHRUNGSFORSCHUNG POTSDAM REHBRUECKE STIFTUNG DES OEFFENTLICHEN RECHTS (DE) | 2018-07-18 | — | — | EP | disclosed |
| US-9631098-B2 | Dispersing agent comprising fillers or pigments | AMRIL AG (CH) | 2017-04-25 | — | — | US | disclosed |
| US-20160230069-A1 | ENVIRONMENTAL FRIENDLY WELL TREATMENT FLUIDS COMPRISING AN ESTER | BANK OF AMERICA, N.A., AS THE ADMINISTRATIVE AGENT | 2016-08-11 | — | — | US | disclosed |
| EP-3024910-A1 | ENVIRONMENTAL FRIENDLY WELL TREATMENT FLUIDS COMPRISING AN ESTER | Amril AG (CH) | 2016-06-01 | — | — | EP | disclosed |
| WO-2015062656-A9 | ENVIRONMENTAL FRIENDLY WELL TREATMENT FLUIDS COMPRISING AN ESTER | AMRIL AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| WO-2008128730-A2 | ANTAGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) | 2008-10-30 | — | — | WO | disclosed |
| EP-1983342-A1 | Antogonists of bitter taste receptors and uses thereof | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand (DE) | 2008-10-22 | — | — | EP | disclosed |
| WO-2008119527-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POSTDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119526-A1 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) | 2008-10-09 | — | — | WO | disclosed |
| EP-1975612-A1 | Agonists of bitter taste receptors and uses thereof | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand (DE) | 2008-10-01 | — | — | EP | disclosed |
| EP-1975611-A1 | Agonists of bitter taste receptors and uses thereof | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand (DE) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007115805-A2 | AURORA KINASE INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007113005-A2 | 2-SUBSTITUTED 3-AMINOSULFONYL-THIOPHENE DERIVATIVES AS AURORA KINASE INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2007-10-11 | — | — | WO | disclosed |