SCHEMBL5158

SCHEMBL5158

[C]1NCCC2CCCC=C12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4555812 0.82
SCHEMBL37555 0.68
SCHEMBL828613 0.65 HRH4 (0.34)
SCHEMBL1650443 0.64 HRH4 (0.37)
SCHEMBL37603 0.64
SCHEMBL8069472 0.63
SCHEMBL168474 0.63
SCHEMBL8690349 0.63
SCHEMBL2361898 0.61
SCHEMBL1586586 0.61 KDM1A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13121 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337220-A1 SELECTIVE, PARTIAL, AND ARRESTIN-BIASED 5-HT2A AGONISTS WITH UTILITY IN VARIOUS DISORDERS Saint Joseph's University (US) 2024-03-20 EP claimed
EP-4232425-A1 CTPS1 INHIBITORS AND USES THEREOF Nimbus Clotho, Inc. (US) 2023-08-30 EP claimed
CN-116601131-A CTPS1 inhibitor and application thereof 林伯士克洛索有限公司 2023-08-15 CN claimed
CN-115819413-A Carbazole-based small-molecule compound, method and organic all-optical synapse based on illumination history-dependent fluorescence intensity mechanism 中国科学院大学 2023-03-21 CN claimed
CN-114763312-A Method for inducing H halogenation in C-H on benzene ring or heterocyclic ring by ultraviolet light 中国科学院大连化学物理研究所 2022-07-19 CN claimed
WO-2022087634-A1 CTPS1 INHIBITORS AND USES THEREOF NIMBUS CLOTHO, INC. (US) 2022-04-28 WO claimed
CN-108368087-B 2, 4-dihydroxy-nicotinamide as APJ agonists 百时美施贵宝公司 2022-04-12 CN claimed
CN-113683616-A KRAS G12C mutein inhibitors 广州百霆医药科技有限公司 2021-11-23 CN claimed
CN-108602813-B Heteroaryl hydroxypyrimidinones as APJ receptor agonists 百时美施贵宝公司 2021-10-29 CN claimed
CN-113527300-A Bruton's tyrosine protein kinase inhibitor 广州百霆医药科技有限公司 2021-10-22 CN claimed
WO-2000047553-A2 ALKENYL AND ALKYNYL COMPOUNDS AS INHIBITORS OF FACTOR Xa COR THERAPEUTICS INC. (US) 2000-08-17 WO claimed
EP-0759917-B1 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES GILEAD SCIENCES INC (US) 2000-04-12 EP claimed
EP-0723533-A1 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-07-31 EP claimed
EP-0665215-A1 1,4-Diamino-2,3-dihydroxybutanes THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-08-02 EP claimed
US-5430155-A Viricides, treatment of AIDS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-07-04 US claimed
WO-1995010506-A1 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-04-20 WO claimed
US-5321023-A Pyridoindolobenzodiazepines and derivatives as antipsychotics THE DU PONT MERCK PHARMACEUTICAL CO. (US) 1994-06-14 US claimed
EP-0532693-A1 1,4-DIAMINO-2,3-DIHYDROXYBUTANES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-03-24 EP claimed
WO-1991018866-A2 1,4-DIAMINO-2,3-DIHYDROXYBUTANES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1991-12-12 WO claimed
US-4604380-A ADMINISTERING TO TREAT BACTERIAL OR MYCOPLASMAL INFECTION ELI LILLY AND COMPANY (US) 1986-08-05 US claimed