SCHEMBL16848801

SCHEMBL16848801

c1cc(-c2ccc(-n3c4ccccc4c4cc(-n5c6ccccc6c6ccccc65)ccc43)cc2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
ATM Q13315 2/20 0.55
KDM4E B2RXH2 1/20 0.55
HDAC4 P56524 1/20 0.41
KMT2A Q03164 2/20 0.39
IL1R1 P14778 1/20 0.39
TSPO P30536 1/20 0.38
ALDH1A1 P00352 2/20 0.38
HTT P42858 2/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
FAAH O00519 1/20 0.38
HSP90AA1 P07900 1/20 0.38
PKM P14618 1/20 0.38
MGLL Q99685 1/20 0.38
RAC2 P15153 1/20 0.36
RAC3 P60763 1/20 0.36
CDC42 P60953 1/20 0.36
RAC1 P63000 1/20 0.36
EDNRB P24530 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24855979 0.97 L3MBTL1 (0.56) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL20047302 0.97 L3MBTL1 (0.56) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL21923155 0.97 L3MBTL1 (0.56) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL22598551 0.97 L3MBTL1 (0.56) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL16171492 0.97 L3MBTL1 (0.56) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL23297733 0.97 L3MBTL1 (0.55) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL24677377 0.97 ATM (0.55) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL17425616 0.97 ATM (0.55) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL23072372 0.95 L3MBTL1 (0.55) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL22598357 0.95 L3MBTL1 (0.55) L3MBTL1ATMKDM4EHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-11485706-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-01 US disclosed
US-9455412-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-09-27 US disclosed
US-9455412-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-09-27 US disclosed
US-20150179948-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-25 US disclosed
US-20150179948-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485706-B2 Organic electroluminescent materials and devices SOD1, L1CAM, EPCAM L3MBTL1 1135/4885ATM 1277/4885KDM4E 3594/4885
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 L3MBTL1 888/4885ATM 3709/4885KDM4E 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.