Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748115 | 0.94 | BACE1 (0.43) | LMNAGAABACE1HSD17B10APP | |
| SCHEMBL20296853 | 0.88 | HSD17B10 (0.56) | LMNAGAABACE1HSD17B10GAPDH | |
| SCHEMBL12152596 | 0.86 | BACE1 (0.47) | LMNAGAABACE1HSD17B10APP | |
| SCHEMBL21558697 | 0.85 | BACE1 (0.59) | LMNAGAABACE1HSD17B10APP | |
| SCHEMBL31621879 | 0.84 | LMNA (0.52) | LMNAGAAHSD17B10MAPTTDP1 | |
| SCHEMBL823757 | 0.84 | LMNA (0.52) | LMNAGAAHSD17B10MAPTTDP1 | |
| SCHEMBL9903140 | 0.83 | BACE1 (0.59) | LMNAGAABACE1CYP2C19MAPT | |
| SCHEMBL16604314 | 0.83 | LMNA (0.42) | LMNAGAABACE1HSD17B10APP | |
| SCHEMBL16748079 | 0.83 | APP (0.39) | APPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL21507746 | 0.82 | HSD17B10 (0.44) | LMNAGAABACE1HSD17B10APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248061-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3248060-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-09-02 | — | — | EP | disclosed |
| US-20200255739-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-08-13 | — | — | US | disclosed |
| US-20200181492-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2020-06-11 | — | — | US | disclosed |
| US-10669484-B2 | Process of preparing a light modulation element | MERCK PATENT GMBH (DE) | 2020-06-02 | — | — | US | disclosed |
| EP-3365411-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| EP-3234689-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-01-29 | — | — | EP | disclosed |
| US-20190292457-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| WO-2019179962-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019030153-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2019-02-14 | — | — | WO | disclosed |
| US-20170357131-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-12-14 | — | — | US | disclosed |
| US-20170351130-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-12-07 | — | — | US | disclosed |
| US-20170343847-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-11-30 | — | — | US | disclosed |
| WO-2017198635-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |
| US-9752075-B2 | Mesogenic media and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-20170190971-A1 | MESOGENIC MEDIA AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-07-06 | — | — | US | disclosed |
| WO-2017067630-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-04-27 | — | — | WO | disclosed |
| US-20160298031-A1 | MESOGENIC MEDIA AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160289561-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-10-06 | — | — | US | disclosed |
| US-20150175886-A1 | MESOGENIC MEDIA AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289561-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | SP1, FOXM1, S100A11 | LMNA 1318/4885GAA 4685/4885BACE1 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.