Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | APAF1 | O14727 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | XBP1 | P17861 | 1/20 | 0.61 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | GALK1 | P51570 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | S100A4 | P26447 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15553849 | 1.00 | PTPRC (0.63) | PTPRCL3MBTL1MEN1APAF1NPC1 | |
| SCHEMBL13820843 | 0.96 | PTPRC (0.63) | PTPRCL3MBTL1MEN1APAF1NPC1 | |
| SCHEMBL1480040 | 0.88 | NPC1 (0.76) | PTPRCL3MBTL1MEN1APAF1NPC1 | |
| SCHEMBL2350060 | 0.88 | NPC1 (0.76) | PTPRCL3MBTL1MEN1APAF1NPC1 | |
| SCHEMBL30481072 | 0.88 | NPC1 (0.76) | PTPRCL3MBTL1MEN1APAF1NPC1 | |
| SCHEMBL1482692 | 0.84 | MEN1 (0.84) | PTPRCL3MBTL1MEN1APAF1NPC1 | |
| SCHEMBL7322266 | 0.84 | MEN1 (0.84) | PTPRCL3MBTL1MEN1APAF1NPC1 | |
| SCHEMBL22797321 | 0.84 | MEN1 (0.70) | PTPRCL3MBTL1MEN1APAF1NPC1 | |
| SCHEMBL15857705 | 0.84 | NPC1 (0.70) | PTPRCL3MBTL1MEN1APAF1NPC1 | |
| SCHEMBL4410719 | 0.84 | MEN1 (0.76) | PTPRCL3MBTL1MEN1APAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9595681-B2 | Compounds and organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |
| US-9595681-B2 | Compounds and organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |
| EP-2875092-B1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20150179953-A1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150179953-A1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150179953-A1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | AFF2, ETV6, PEF1 | PTPRC 3195/4885L3MBTL1 2796/4885MEN1 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.