SCHEMBL1480040

SCHEMBL1480040

O=C1c2cc(-c3ccc(-c4ccccc4)cc3)ccc2-c2ccc(-c3ccc(-c4ccccc4)cc3)cc21

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.76
SMN1; SMN2 Q16637 3/20 0.76
MEN1 O00255 2/20 0.76
MAPT P10636 2/20 0.76
KMT2A Q03164 2/20 0.76
RAB9A P51151 2/20 0.76
APAF1 O14727 1/20 0.76
LMNA P02545 1/20 0.76
THRB P10828 1/20 0.76
XBP1 P17861 1/20 0.76
PTBP1 P26599 1/20 0.76
HTT P42858 1/20 0.76
GALK1 P51570 1/20 0.76
BLM P54132 1/20 0.76
SMAD3 P84022 1/20 0.76
ATM Q13315 1/20 0.76
NPSR1 Q6W5P4 1/20 0.76
L3MBTL1 Q9Y468 1/20 0.76
MAOA P21397 2/20 0.55
MAOB P27338 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30481072 1.00 NPC1 (0.76) NPC1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL2350060 1.00 NPC1 (0.76) NPC1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL1482692 0.96 MEN1 (0.84) NPC1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL22797321 0.96 MEN1 (0.70) NPC1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL15857705 0.96 NPC1 (0.70) NPC1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL7322266 0.96 MEN1 (0.84) NPC1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL15383588 0.95 MEN1 (0.83) NPC1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL4410719 0.95 MEN1 (0.76) NPC1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL57813 0.93 NPC1 (0.80) NPC1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL21993324 0.93 NPC1 (0.80) NPC1SMN1; SMN2MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed