Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.84 |
| ▸ | NPC1 | O15118 | 4/20 | 0.84 |
| ▸ | RAB9A | P51151 | 4/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.84 |
| ▸ | APAF1 | O14727 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 3/20 | 0.84 |
| ▸ | HTT | P42858 | 3/20 | 0.84 |
| ▸ | GALK1 | P51570 | 3/20 | 0.84 |
| ▸ | BLM | P54132 | 3/20 | 0.84 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.84 |
| ▸ | MAPT | P10636 | 2/20 | 0.84 |
| ▸ | THRB | P10828 | 2/20 | 0.84 |
| ▸ | PTBP1 | P26599 | 2/20 | 0.84 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.84 |
| ▸ | XBP1 | P17861 | 1/20 | 0.84 |
| ▸ | ATM | Q13315 | 1/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.84 |
| ▸ | PTPRC | P08575 | 9/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1482692 | 1.00 | MEN1 (0.84) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL57813 | 0.98 | NPC1 (0.80) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30722379 | 0.98 | NPC1 (0.80) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21993324 | 0.98 | NPC1 (0.80) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19001850 | 0.96 | NPC1 (0.78) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19001853 | 0.96 | NPC1 (0.78) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL978978 | 0.96 | NPC1 (0.92) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28198235 | 0.96 | MEN1 (0.92) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2350060 | 0.96 | NPC1 (0.76) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4410719 | 0.96 | MEN1 (0.76) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3238286-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2024-01-17 | — | — | EP | disclosed |
| US-20230126850-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230126850-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-04-27 | — | — | US | disclosed |
| EP-3512841-B1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | MERCK PATENT GMBH (DE) | 2023-04-26 | — | — | EP | disclosed |
| US-11545634-B2 | Heterocyclic spiro compounds | MERCK PATENT GMBH (DE) | 2023-01-03 | — | — | US | disclosed |
| US-11512204-B2 | Squarylium dye and composition containing same | TOYO INK SC HOLDINGS CO., LTD. (JP) | 2022-11-29 | — | — | US | disclosed |
| US-11447464-B2 | Compounds with spirobifluorene-structures | MERCK PATENT GMBH (DE) | 2022-09-20 | — | — | US | disclosed |
| CN-108368054-B | Material for organic electroluminescent device | 默克专利有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114763340-A | Organic compound, application and preparation method thereof, and organic electroluminescent device using organic compound | 北京鼎材科技有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-114127638-A | Negative photosensitive resin composition, cured film, organic EL display, and method for producing cured film | 东丽株式会社 | 2022-03-01 | — | — | CN | disclosed |
| US-20160268509-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| WO-2016131521-A1 | SPIROBIFLUORENE DERIVATIVE-BASED MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | WO | disclosed |
| US-20160190466-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-30 | — | — | US | disclosed |
| US-20160190466-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-30 | — | — | US | disclosed |
| WO-2016078738-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-05-26 | — | — | WO | disclosed |
| US-20150337197-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150337197-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447464-B2 | Compounds with spirobifluorene-structures | SLCO1B3, SLCO4C1, SLCO1B1 | MEN1 1205/4885KMT2A 3037/4885NPC1 519/4885 |
| US-11545634-B2 | Heterocyclic spiro compounds | NES, KCNC1, HCN4 | MEN1 1660/4885KMT2A 3328/4885NPC1 2116/4885 |
| US-20160190466-A1 | MATERIALS FOR ELECTRONIC DEVICES | SDHB, SDHA, ETFB | MEN1 337/4885KMT2A 2173/4885NPC1 3354/4885 |
| US-20160268509-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, GPX1, EPN1 | MEN1 345/4885KMT2A 1551/4885NPC1 2849/4885 |
| US-20230126850-A1 | HETEROCYCLIC SPIRO COMPOUNDS | NES, KCNC1, HCN4 | MEN1 1660/4885KMT2A 3328/4885NPC1 2116/4885 |
| US-20150337197-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EML4, L1CAM | MEN1 1571/4885KMT2A 2434/4885NPC1 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.