Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852800 | 0.80 | GRIA2 (0.36) | GRIA2 | |
| SCHEMBL16852807 | 0.72 | CA1 (0.39) | GRIA2 | |
| SCHEMBL18186782 | 0.70 | KEAP1 (0.41) | GRIA2 | |
| SCHEMBL30620251 | 0.68 | CAPN1 (0.35) | GRIA2 | |
| SCHEMBL20269098 | 0.68 | CAPN1 (0.35) | GRIA2 | |
| SCHEMBL20283264 | 0.68 | CAPN1 (0.35) | GRIA2 | |
| SCHEMBL18733699 | 0.68 | CAPN1 (0.35) | GRIA2 | |
| SCHEMBL31306077 | 0.68 | CAPN1 (0.35) | GRIA2 | |
| SCHEMBL20284973 | 0.67 | PSEN1 (0.35) | GRIA2ACHE | |
| SCHEMBL710185 | 0.65 | KEAP1 (0.50) | GRIA2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015092713-A1 | NRF2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-06-25 | — | — | WO | disclosed |