Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18733699 | 0.85 | CAPN1 (0.35) | GRIA2CA1CA2OPRM1OPRL1 | |
| SCHEMBL30620251 | 0.85 | CAPN1 (0.35) | GRIA2CA1CA2OPRM1OPRL1 | |
| SCHEMBL20283264 | 0.85 | CAPN1 (0.35) | GRIA2CA1CA2OPRM1OPRL1 | |
| SCHEMBL31306077 | 0.85 | CAPN1 (0.35) | GRIA2CA1CA2OPRM1OPRL1 | |
| SCHEMBL20269098 | 0.85 | CAPN1 (0.35) | GRIA2CA1CA2OPRM1OPRL1 | |
| SCHEMBL16852807 | 0.80 | CA1 (0.39) | GRIA2CA1CA2OPRL1KEAP1 | |
| SCHEMBL16852949 | 0.80 | GRIA2 (0.33) | GRIA2 | |
| SCHEMBL20284973 | 0.74 | PSEN1 (0.35) | GRIA2CA1CA2OPRM1OPRL1 | |
| SCHEMBL16831955 | 0.70 | CA1 (0.41) | GRIA2CA1CA2OPRM1KEAP1 | |
| SCHEMBL18325510 | 0.70 | PNMT (0.46) | MTNR1AMTNR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015092713-A1 | NRF2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-06-25 | — | — | WO | disclosed |