Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 19/20 | 1.00 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18145300 | 0.99 | ADRA1A (0.98) | ADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL16854407 | 0.81 | ADRA1A (1.00) | ADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL16854291 | 0.81 | ADRA1A (1.00) | ADRA1A | |
| SCHEMBL16823907 | 0.79 | ADRA1A (0.65) | ADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL16854330 | 0.78 | ADRA1A (1.00) | ADRA1A | |
| SCHEMBL16854290 | 0.77 | ADRA1A (0.73) | ADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL16827298 | 0.77 | ADRA1A (0.73) | ADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL16827277 | 0.77 | ADRA1A (0.73) | ADRA1AL3MBTL3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL18145307 | 0.76 | ADRA1A (0.72) | ADRA1AL3MBTL3L3MBTL1 | |
| SCHEMBL16854630 | 0.76 | ADRA1A (1.00) | ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624199-B2 | Substituted bipiperidinyl derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-18 | — | — | US | disclosed |
| US-9624199-B2 | Substituted bipiperidinyl derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-18 | — | — | US | disclosed |
| WO-2015091420-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES AS ADRENORECEPTOR ALPHA 2C ANTAGONISTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |