Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 19/20 | 1.00 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16854330 | 0.84 | ADRA1A (1.00) | ADRA1AGRM5 | |
| SCHEMBL16823944 | 0.82 | ADRA1A (0.70) | ADRA1A | |
| SCHEMBL16854292 | 0.81 | ADRA1A (1.00) | ADRA1A | |
| SCHEMBL31047819 | 0.80 | ADRA1A (1.00) | ADRA1A | |
| Hydrochloric Acid SCHEMBL18145300 | 0.80 | ADRA1A (0.98) | ADRA1A | |
| SCHEMBL16846239 | 0.80 | ADRA1A (1.00) | ADRA1A | |
| SCHEMBL16854327 | 0.79 | ADRA1A (1.00) | ADRA1AGRM5 | |
| SCHEMBL18145306 | 0.79 | ADRA1A (1.00) | ADRA1AGRM5 | |
| SCHEMBL16845199 | 0.78 | ADRA1A (0.64) | ADRA1A | |
| SCHEMBL16827277 | 0.78 | ADRA1A (0.73) | ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624199-B2 | Substituted bipiperidinyl derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-18 | — | — | US | disclosed |
| US-9624199-B2 | Substituted bipiperidinyl derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-18 | — | — | US | disclosed |
| US-9624199-B2 | Substituted bipiperidinyl derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-18 | — | — | US | disclosed |
| US-20160304492-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-10-20 | — | — | US | disclosed |
| WO-2015091420-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES AS ADRENORECEPTOR ALPHA 2C ANTAGONISTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304492-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | TNNC1, TNNI3, FABP3 | ADRA1A 1176/4885GRM5 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.