Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16832554 | 0.88 | RAB9A (0.57) | ALDH1A1RAB9ANPC1KDM4ELMNA | |
| SCHEMBL16855655 | 0.82 | RAB9A (0.58) | ALDH1A1RAB9ANPC1KDM4ELMNA | |
| SCHEMBL18483510 | 0.80 | CYP11B1 (0.44) | NR3C1CYP11B1KDM4ELMNAGAA | |
| SCHEMBL16832607 | 0.78 | GAA (0.58) | NR3C1CYP11B1KDM4EGAA | |
| SCHEMBL16855481 | 0.78 | GAA (0.57) | ALDH1A1LMNAHTTGAAPTGDR2 | |
| SCHEMBL16855652 | 0.77 | SLC2A1 (0.58) | ALDH1A1NPC1KDM4ELMNAHTT | |
| SCHEMBL16855410 | 0.77 | ALDH1A1 (0.50) | ALDH1A1RAB9ANPC1KDM4ELMNA | |
| SCHEMBL16855660 | 0.77 | GAA (0.56) | ALDH1A1RAB9ALMNAHTTL3MBTL1 | |
| SCHEMBL18485353 | 0.76 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1LMNAMAPK1 | |
| SCHEMBL16832375 | 0.76 | RAB9A (0.42) | ALDH1A1RAB9ANPC1NR3C1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015091428-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |