Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082853 | 0.87 | KDM4E (0.59) | PTGDR2GAAPOLBKDM4EALDH1A1 | |
| SCHEMBL16855405 | 0.86 | POLB (0.43) | PTGDR2GAAGFERSLC2A1POLB | |
| SCHEMBL16855650 | 0.82 | ALDH1A1 (0.45) | GAAPOLBKDM4ERECQLSMN1; SMN2 | |
| SCHEMBL16855657 | 0.81 | PTGDR2 (0.47) | PTGDR2SLC2A1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL16855654 | 0.75 | KDM4E (0.56) | PTGDR2GAAPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL16832454 | 0.75 | GAA (0.78) | PTGDR2GAAGFERSLC2A1POLB | |
| SCHEMBL31673675 | 0.73 | POLB (0.80) | PTGDR2GAAPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL15445673 | 0.72 | GAA (0.47) | PTGDR2GAAGFERSLC2A1POLB | |
| SCHEMBL7108739 | 0.72 | POLB (0.60) | PTGDR2GAAPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL16832611 | 0.72 | LMNA (0.57) | GAAPOLBSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015091428-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |