Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16834804 | 0.86 | MAPT (0.57) | SMN1; SMN2HPGDLMNAMAPTTSHR | |
| SCHEMBL6320208 | 0.86 | KCNH2 (0.48) | SMN1; SMN2LMNAMAPTNPC1RAB9A | |
| SCHEMBL6201913 | 0.81 | NPC1 (0.64) | ALDH1A1GAASMN1; SMN2LMNAMAPT | |
| SCHEMBL7127948 | 0.80 | LMNA (0.62) | ALDH1A1GAASMN1; SMN2HPGDLMNA | |
| SCHEMBL16661979 | 0.80 | SMN1; SMN2 (0.54) | GAASMN1; SMN2LMNA | |
| SCHEMBL3190220 | 0.78 | ALOX15 (0.61) | GAASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL10289328 | 0.78 | PPARA (0.55) | ALDH1A1GAASMN1; SMN2HPGDMAPT | |
| SCHEMBL4841249 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1GAASMN1; SMN2LMNAMEN1 | |
| SCHEMBL10967799 | 0.77 | SMN1; SMN2 (0.57) | GAASMN1; SMN2 | |
| SCHEMBL10967825 | 0.77 | SMN1; SMN2 (0.54) | ALDH1A1GAASMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015089800-A1 | FLUOROPHENYL PYRAZOL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2015-06-25 | — | — | WO | disclosed |