Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685656 | 0.80 | BTN3A1 (0.44) | ALOX15ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL6244415 | 0.78 | ALOX15 (0.41) | ALOX15ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL955895 | 0.75 | — | — | |
| SCHEMBL6232511 | 0.74 | ALDH1A1 (0.33) | ALOX15ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL113776 | 0.74 | — | — | |
| SCHEMBL1871028 | 0.74 | ALDH1A1 (0.65) | ALOX15ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL6913629 | 0.74 | ALDH1A1 (0.48) | ALOX15ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL7094910 | 0.73 | CYP3A4 (0.41) | ALDH1A1 | |
| SCHEMBL27752278 | 0.73 | ALOX15 (0.44) | ALOX15ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL30303220 | 0.72 | ALDH1A1 (0.37) | ALOX15ALDH1A1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1950208-B1 | PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE | SUMITOMO CHEMICAL CO (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-7928253-B2 | Method of producing 6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20100168463-A1 | METHOD OF PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-01 | — | — | US | disclosed |
| EP-1950208-A1 | PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE | Sumitomo Chemical Company, Limited (JP) | 2008-07-30 | — | — | EP | disclosed |
| EP-0968170-A1 | METHODS FOR PREPARING PRENYL ALCOHOL | LOYOLA UNIVERSITY OF CHICAGO (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5872277-A | Methods for preparing prenyl alcohol | LOYOLA UNIVERSITY OF CHICAGO (US) | 1999-02-16 | — | — | US | disclosed |
| WO-1998040345-A1 | METHODS FOR PREPARING PRENYL ALCOHOL | LOYOLA UNIVERSITY OF CHICAGO (US) | 1998-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168463-A1 | METHOD OF PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE | CYP1B1, HACL2, CMA1 | ALOX15 650/4885ALDH1A1 147/4885MMP1 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.