⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706691 | 0.81 | — | — | |
| SCHEMBL929339 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL6708436 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL6706823 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL6708448 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL1123036 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL1286895 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL703383 | 0.76 | — | — | |
| SCHEMBL7764321 | 0.75 | — | — | |
| SCHEMBL17937703 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2889617-B1 | ANTIBODY PURIFICATION METHOD BY MEANS OF TEMPERATURE-RESPONSIVE CHROMATOGRAPHY | ASAHI KASEI MEDICAL CO LTD (JP) | 2017-10-11 | — | — | EP | disclosed |
| US-20150218208-A1 | METHOD FOR PURIFYING ANTIBODY BY TEMPERATURE-RESPONSIVE CHROMATOGRAPHY | ASAHI KASEI MEDICAL CO., LTD. (JP) | 2015-08-06 | — | — | US | disclosed |
| EP-2889617-A1 | ANTIBODY PURIFICATION METHOD BY MEANS OF TEMPERATURE-RESPONSIVE CHROMATOGRAPHY | Asahi Kasei Medical Co., Ltd. (JP) | 2015-07-01 | — | — | EP | disclosed |