Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | SRC | P12931 | 4/20 | 0.43 |
| ▸ | ABL2 | P42684 | 3/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.40 |
| ▸ | FYN | P06241 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618779 | 0.77 | ADORA2A (0.59) | ADORA2APIK3CAPIK3CGHRH2HRH3 | |
| SCHEMBL16857690 | 0.76 | FEN1 (0.34) | ABL1EGFRSRCPIK3CDHCK | |
| SCHEMBL145785 | 0.72 | SRC (0.56) | GAAABL1EGFRSRCABL2 | |
| SCHEMBL2405655 | 0.69 | KDM1A (0.46) | ADORA2ALRRK2FYNPIK3CGHRH2 | |
| SCHEMBL3766647 | 0.67 | LRRK2 (0.61) | GAAADORA2ALRRK2ALDH1A1ALOX5 | |
| SCHEMBL14985513 | 0.67 | MEN1 (0.57) | GAAADORA2AALDH1A1HTTHIF1A | |
| SCHEMBL15117084 | 0.66 | ADORA2A (0.65) | GAAADORA2AALDH1A1HTTHIF1A | |
| SCHEMBL16654524 | 0.65 | ADORA2A (0.42) | GAABTKADORA2APIK3CGHRH2 | |
| SCHEMBL5753689 | 0.65 | DPP4 (0.56) | GAAADORA2APIK3CAPIK3CGHRH2 | |
| SCHEMBL29930966 | 0.65 | KIT (0.50) | GAABTKADORA2AALDH1A1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408772-B1 | COMPOUNDS | MEDICAL RES COUNCIL TECHNOLOGY (GB) | 2015-07-01 | — | — | EP | disclosed |