Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.59 |
| ▸ | HRH2 | P25021 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 4/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030372 | 0.86 | DHFR (0.46) | ADORA2AADORA1HRH2HRH3ALOX5AP | |
| SCHEMBL1033184 | 0.85 | DHFR (0.45) | ADORA2AADORA1HRH2HRH3ALOX5AP | |
| SCHEMBL16857688 | 0.77 | GAA (0.45) | ADORA2AADORA1HRH2HRH3PIK3CG | |
| SCHEMBL3620507 | 0.76 | TNK2 (0.47) | HRH3MAPTFEN1 | |
| SCHEMBL2405655 | 0.75 | KDM1A (0.46) | ADORA2AADORA1HRH2HRH3ADORA2B | |
| SCHEMBL20150248 | 0.73 | ADORA2A (0.60) | ADORA2AADORA1PIK3CG | |
| SCHEMBL5753689 | 0.73 | DPP4 (0.56) | ADORA2AADORA1HRH2HRH3ADORA2B | |
| SCHEMBL27964932 | 0.73 | ADORA2A (0.61) | ADORA2AADORA1HRH2HRH3ADORA2B | |
| SCHEMBL13723740 | 0.72 | ADORA2A (0.60) | ADORA2AADORA1HRH2HRH3ADORA2B | |
| SCHEMBL14983456 | 0.71 | PIK3CG (0.62) | ADORA2AADORA1HRH2HRH3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151747-A1 | PYRIMINE COMPOUNDS AND METHODS OF MAKING AND USING SAME | CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |