SCHEMBL16857741

SCHEMBL16857741

Cc1cc2nc(-n3cc(OC(=O)O)cn3)[nH]c(=O)c2cc1Oc1c(C)cccc1C

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16857906 0.92 EGLN1 (0.53) EGLN1
SCHEMBL16857779 0.92 EGLN1 (0.47) EGLN1
SCHEMBL16857893 0.92 EGLN1 (0.47) EGLN1
SCHEMBL16857867 0.91 EGLN1 (0.50) EGLN1
SCHEMBL16857730 0.89 EGLN1 (0.52) EGLN1
SCHEMBL16857909 0.88 EGLN1 (0.48) EGLN1
SCHEMBL16857915 0.87 EGLN1 (0.44) EGLN1
SCHEMBL3020578 0.87 EGLN1 (0.65) EGLN1
SCHEMBL16857884 0.87 EGLN1 (0.44) EGLN1
SCHEMBL16857701 0.86 MGLL (0.45) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2396316-B1 QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2015-07-01 EP claimed