Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857747 | 0.91 | MGLL (0.45) | MGLLEGLN1ICAM1SELE | |
| SCHEMBL3040905 | 0.89 | EGLN1 (0.55) | MGLLEGLN1 | |
| SCHEMBL16857867 | 0.89 | EGLN1 (0.50) | MGLLEGLN1 | |
| SCHEMBL16857736 | 0.88 | MGLL (0.52) | MGLLEGLN1 | |
| SCHEMBL16857909 | 0.88 | EGLN1 (0.48) | MGLLEGLN1 | |
| SCHEMBL16857915 | 0.86 | EGLN1 (0.44) | EGLN1 | |
| SCHEMBL16857741 | 0.86 | EGLN1 (0.49) | EGLN1 | |
| SCHEMBL16857884 | 0.84 | EGLN1 (0.44) | MGLLEGLN1 | |
| SCHEMBL16857833 | 0.82 | EGLN1 (0.51) | MGLLEGLN1 | |
| SCHEMBL16857895 | 0.81 | EGLN1 (0.41) | MGLLEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |