Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | PARG | Q86W56 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857787 | 0.90 | EGLN1 (0.50) | EGLN1MMP13 | |
| SCHEMBL16551342 | 0.88 | EGLN1 (0.72) | EGLN1 | |
| SCHEMBL16857733 | 0.86 | PARG (0.43) | EGLN1PARG | |
| SCHEMBL16857880 | 0.85 | EGLN1 (0.44) | EGLN1 | |
| SCHEMBL16857900 | 0.85 | EGLN1 (0.52) | EGLN1 | |
| SCHEMBL16857699 | 0.84 | EGLN1 (0.56) | EGLN1 | |
| SCHEMBL3030587 | 0.84 | EGLN1 (0.77) | EGLN1 | |
| SCHEMBL16857877 | 0.83 | EGLN1 (0.47) | EGLN1 | |
| SCHEMBL16857839 | 0.83 | EGLN1 (0.52) | EGLN1 | |
| SCHEMBL16857888 | 0.83 | EGLN1 (0.52) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |