Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 16/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857781 | 0.90 | EGLN1 (0.55) | EGLN1MMP13 | |
| SCHEMBL16857773 | 0.88 | EGLN1 (0.56) | EGLN1MMP13 | |
| SCHEMBL16857786 | 0.88 | EGLN1 (0.57) | EGLN1MMP13 | |
| SCHEMBL3035391 | 0.87 | EGLN1 (0.66) | EGLN1 | |
| SCHEMBL16857879 | 0.87 | EGLN1 (0.55) | EGLN1MMP13 | |
| SCHEMBL16857755 | 0.86 | EGLN1 (0.52) | EGLN1MMP13 | |
| SCHEMBL16857870 | 0.85 | EGLN1 (0.51) | EGLN1 | |
| SCHEMBL16857838 | 0.85 | EGLN1 (0.51) | EGLN1 | |
| SCHEMBL16857726 | 0.84 | EGLN1 (0.56) | EGLN1 | |
| SCHEMBL16857737 | 0.83 | EGLN1 (0.53) | EGLN1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |