Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD2 | O60906 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27779216 | 0.85 | SMPD2 (0.38) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL30401308 | 0.85 | TSHR (0.47) | SMPD2ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL7420130 | 0.84 | CYP1A2 (0.48) | NPSR1ALDH1A1CYP1A2 | |
| SCHEMBL3272399 | 0.84 | NPC1 (0.44) | ALDH1A1KMT2ANPC1POLBHTT | |
| SCHEMBL7420127 | 0.84 | CYP1A2 (0.48) | NPSR1ALDH1A1CYP1A2 | |
| SCHEMBL21776703 | 0.80 | NPSR1 (0.41) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL3286896 | 0.79 | NPC1 (0.48) | ALDH1A1NPC1RAB9AGLATSHR | |
| SCHEMBL3286898 | 0.79 | NPC1 (0.48) | ALDH1A1NPC1RAB9AGLATSHR | |
| SCHEMBL29442908 | 0.78 | NPSR1 (0.40) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10381409 | 0.77 | ALDH1A1 (0.41) | SMPD2NPSR1ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604697-B1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2015-07-01 | — | — | EP | claimed |