Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819566 | 0.85 | CPA3 (0.46) | NPC1RAB9AALDH1A1GLAHTT | |
| SCHEMBL5819570 | 0.85 | CPA3 (0.46) | NPC1RAB9AALDH1A1GLAHTT | |
| SCHEMBL16858005 | 0.84 | SMPD2 (0.39) | NPC1RAB9AALDH1A1GLAHTT | |
| SCHEMBL28654510 | 0.82 | LMNA (0.42) | NPC1RAB9AALDH1A1GLAHTT | |
| SCHEMBL30401308 | 0.81 | TSHR (0.47) | NPC1RAB9AALDH1A1GLASMN1; SMN2 | |
| SCHEMBL27779216 | 0.81 | SMPD2 (0.38) | NPC1RAB9AALDH1A1GLAHTT | |
| SCHEMBL11189169 | 0.80 | NPC1 (0.47) | NPC1RAB9AALDH1A1GLAHTT | |
| SCHEMBL2855957 | 0.80 | KMT2A (0.49) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL3126212 | 0.80 | KMT2A (0.49) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL3126205 | 0.80 | KMT2A (0.49) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687435-B2 | Benzoyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20070142230-A1 | Benzoyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-21 | — | — | US | disclosed |
| US-20070060480-A1 | Heteroaroyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
| EP-0079390-B1 | PROCESS FOR PREPARING BETA-HYDROXY AMINO ACID | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-12-27 | — | — | EP | disclosed |
| EP-0079390-A1 | PROCESS FOR PREPARING BETA-HYDROXY AMINO ACID | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1983-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142230-A1 | Benzoyl-substituted phenylalanineamides | PAH, TYR, BCAT2 | NPC1 3822/4885RAB9A 2967/4885ALDH1A1 1239/4885 |
| US-20070060480-A1 | Heteroaroyl-substituted phenylalanineamides | PAH, PM20D2, FARSA | NPC1 4345/4885RAB9A 1587/4885ALDH1A1 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.